Focal Points 2020 Module: Corneal Melts: Treatment, Management, and Sequelae

CME Credit
  • Up to 2.0 credits of General CME
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Focal Points 2020 Module: Corneal Melts: Treatment, Management, and Sequelae

Focal Points 2020 Module: Corneal Melts: Treatment, Management, and Sequelae

Corneal melting, also termed corneal ulceration or keratolysis, is defined by loss of epithelium and the underlying stromal tissue. The disease process can be both frustrating to the clinician and visually devastating to the patients and is often difficult to treat.

Important etiologies known to cause corneal melting include autoimmune disease, neurotrophic keratitis, thermal burns, chemical injuries, mechanical damage, limbal stem cell deficiency (LSCD), and infections. Various treatments have proven successful for broad categories of corneal melting, but there are also new management techniques that are geared toward specific disease processes.

This Focal Points module reviews the many complexities of treating and managing corneal melts as there is no single treatment for any specific disease entity, and what works for one patient in a particular disease state may not work for a different patient with the same underlying pathology.

By completing this module, you will be able to:

  • Identify the underlying etiologies and disease states associated with corneal melt.
  • Describe the variety of amniotic membranes available and the various scenarios in which they are used.
  • Evaluate the current literature aimed at understanding the best approach to limbal stem cell transplantation.
  • Discuss why both nerve growth factor and corneal neurotization are gaining traction as treatments for neurotrophic keratitis.
  • Describe clinical scenarios in which patients may benefit from the use of scleral lenses to treat corneal melting.
  • Summarize generalized approaches to corneal melting as well as etiology-specific treatments.

Authors: Ashlie Bernhisel, MD and Natalie Afshari, MD

Focal Points issues review the most crucial advances and feature insights to help you integrate tested findings into your practice.

Subscribers receive 12 issues a year, plus access to the Focal Points digital archive.

This issue includes an audio version. To access the audio version of this module, scan the QR code in the print module or click the link within the digital module.

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CME Information
The American Academy of Ophthalmology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The American Academy of Ophthalmology designates this enduring material for a maximum of 2 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

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