Focal Points 2019 Module: Stem Cell-Based Therapy for Retinal Degenerative Disease

CME Credit
  • Up to 2.0 credits of General CME
Product Number

Media Type: eBook

Availability: In stock

93% of 100
Product Selection Member Price Nonmember Price Qty
$30.00 $50.00

Focal Points 2019 Module: Stem Cell-Based Therapy for Retinal Degenerative Disease

Focal Points 2019 Module: Stem Cell-Based Therapy for Retinal Degenerative Disease

Over the past several decades, significant advances in stem cell biology have allowed the creation of cell replacement strategies to treat retinal degenerative diseases. Embryonic stem cells and induced pluripotent stem cells have become promising sources of a variety of retinal tissue components.

Age-related macular degeneration has received attention as a target disease because of the large unmet medical need associated with non-neovascular AMD. While AMD is a multifactorial disease, the dysfunction and ultimate loss of the retinal pigment epithelium is a major milestone in the progression of the disease and is highly correlated with vision loss.

Based on current clinical trials, it’s clear that stem cell–derived RPE transplantation in the subretinal space is possible and offers a potential therapy for disorders impacting the RPE.

This Focal Points module lists possible stem cell sources, discusses the surgical approaches used in recent retinal cell–based therapy clinical trials and examines the potential risks of the reviewed therapies.

By completing this module, you will be able to:

  • List the potential sources of stem cells for use in retinal cell–based therapy.
  • Describe the different formulations of stem cells used in recent clinical trials.
  • Describe the different surgical approaches for delivery of stem cell–based therapy to the posterior pole.
  • Discuss the potential risks of stem cell–based therapies.

Authors: Jeremy Uang, BS; Amir H. Kashani, MD, PhD

Focal Points issues review the most crucial advances and feature insights to help you integrate tested research into your practice.

Subscribers receive 12 issues a year, plus access to the Focal Points digital archive.

This issue includes an audio version.

To access the audio version of this module, scan the QR code in the print module or click the link within the digital module.

To access this issue from your laptop or desktop computer, log in to aao.org/myonlineproducts with your Academy username and password.

To access this issue from your smartphone or tablet, use the free AAO eBooks app. For eBook features, requirements and licensing, visit: aao.org/ebooks. Please allow up to 90 minutes for receiving an access key (via email) that will allow you to retrieve your eBook after purchase.

CME Information
The American Academy of Ophthalmology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The American Academy of Ophthalmology designates this enduring material for a maximum of 2 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Write Your Own Review
Only registered users can write reviews. Please Sign in or create an account
For eBook features, requirements and licensing, visit: https://store.aao.org/ebooks-instructions.
© 2019, American Academy of Ophthalmology