Fundus autofluorescence is a vital tool that can be used to evaluate a variety of retinal diseases that involve abnormal fluorophore accumulation or the loss of fluorophores. FAF allows you to see details that may not be clinically visible and can aid in the diagnosis, documentation and assessment of disease. New techniques like the ability to quantitate the FAF signal may allow deeper understanding of these conditions and improve our ability to predict their course.
This Focal Points module outlines the primary ways to capture FAF images: traditional fundus camera with special filters, an imaging system based on confocal scanning laser ophthalmoscopy and the relatively new wide-field systems. How FAF use can be applied to the diagnosis and treatment of various conditions, including age-related macular degeneration, Stargardt disease, Best disease and retinal pigment epithelium are also discussed.
Complete this module to:
- State the basis of autofluorescence imaging in the retina.
- List the capabilities and limitations of capturing systems.
- Summarize the clinical applications of autofluorescence imaging.
Authors: Mayss Al-Sheikh, MD; Phillip Phuc Le, MD, PhD; SriniVas R. Sadda, MD
Consultants: Amani A. Fawzi, MD; Richard F. Spaide, MD
Focal Points issues are practical, hands-on discussions of the clinical issues you face daily. Each issue delivers high-quality, trusted ophthalmic information written and reviewed by leading experts.
Subscribers receive 12 issues a year, plus access to the Focal Points digital archive.
To access this issue from your laptop or desktop computer, log in to www.aao.org/myonlineproducts with your Academy username and password.
To access this issue from your smartphone or tablet, use the free AAO eBooks app.
The American Academy of Ophthalmology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
The American Academy of Ophthalmology designates this enduring material for a maximum of 2 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.