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Hereditary maculopathies consist of a diverse group of disorders that affect central vision, with variable degrees of degeneration of the macula and retinal pigment epithelium (RPE). Molecular genetics has become increasingly useful in terms of disease categorization, diagnosis, and prognosis. This issue summarizes clinical features, study results, prognoses, and current molecular genetic discoveries pertaining to the most common and well-understood hereditary maculopathies.
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